ASB1

Across TCGA pan-cancer cohorts, ASB1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ASB1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ASB1 RNA is repressed in tumor relative to normal tissue. In most cancer types ASB1 is over-expressed in tumor, although a few such as THCA and BLCA show the opposite, repressed pattern.

THCA, BLCA, and LIHC are the cancer types where ASB1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASB1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.732	<.001	9	view →
BLCA	Male	IV	−2.080	.001	8	view →
LIHC	Male	III,IV	+0.944	<.001	8	view →
KIRC	Male	II,III,IV	−0.587	<.001	8	view →
BRCA	All	III,IV	−1.139	<.001	6	view →
KIRP	Male	II,III,IV	−0.666	.001	6	view →
CHOL	Male	All	+2.623	<.001	5	view →
KICH	All	All	−0.549	<.001	5	view →
HNSC	All	III,IV	+0.434	.005	5	view →
COAD	Female	All	+0.348	.010	5	view →
UCEC	All	All	−1.003	<.001	4	view →
READ	Male	All	+0.470	.007	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ASB1–THCA

Open the THCA breakdown →