ASAP3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ASAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,600 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASAP3-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of proteasomal protein catabolic process, and Negative regulation of myoblast fusion. Each is linked with ASAP3 in more than 14 cancer types. Because this analysis shows association rather than direction, both ASAP3-to-partner and partner-to-ASAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ASAP3-low versus ASAP3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAP3→partner) and Y-score (partner→ASAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSNegative regulation of syncytium formation by plasma membrane fusion →+0.164+1.863.001<.001315
OESOPHAGUSRegulation of proteasomal protein catabolic process →+0.093+1.453<.001.006313
OESOPHAGUSNegative regulation of myoblast fusion →+0.158+1.863.001<.001313
STOMACHGolgi vesicle transport →+0.085+1.899.001.001313
STOMACHVacuole organization →+0.079+2.067<.001<.001313
OVARYProcess utilizing autophagic mechanism →+0.058+1.602<.001.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,600 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ASAP3 expression — OESOPHAGUS

Box plot of Negative regulation of syncytium formation by plasma membrane fusion in ASAP3-low vs ASAP3-high samples in OESOPHAGUS.

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