ASAP3

Across TCGA cell cohorts, ASAP3 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASAP3-associated genes across cancer lineages are PGK2, S100A12, and BPIFC. Each is linked with ASAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASAP3-to-partner and partner-to-ASAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGK2 grouped by ASAP3-low versus ASAP3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAP3→partner) and Y-score (partner→ASAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PGK2 →	+0.209	+4.930	<.001	.008	3	1
OVARY	S100A12 →	+0.829	+3.938	<.001	.005	3	1
OVARY	BPIFC →	+0.146	+4.070	<.001	.003	3	1
LUNG_NSCLC_LUAD	CABS1 →	+0.012	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR56B1 →	+0.048	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP17-1 →	+0.021	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

PGK2 by ASAP3 expression — SOFT_TISSUE

Explore this box plot interactively →