ASAP1

Across TCGA pan-cancer cohorts, ASAP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASAP1 data layer compared with 30 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ASAP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASAP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

COAD, LUAD, and CCRCC are the cancer types where ASAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.891	1.000	.035	18	view →
LUAD	DFS	Tertile	II,III,IV	0.822	0.169	.003	17	view →
CCRCC	OS	Median	III,IV	0.795	0.964	.026	2	view →
PDAC	OS	Quartile	All	0.310	0.503	.034	2	view →
HNSC	DFS	Quartile	All	0.885	0.735	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASAP1–COAD (DFS)

Open the COAD breakdown →