ASAP1

Across TCGA cell cohorts, ASAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,446 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASAP1-associated GO terms across cancer lineages are Positive regulation of membrane tubulation, Regulation of cell-substrate junction organization, and Positive regulation of cell-substrate junction organization. Each is linked with ASAP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ASAP1-to-partner and partner-to-ASAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of membrane tubulation grouped by ASAP1-low versus ASAP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAP1→partner) and Y-score (partner→ASAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of membrane tubulation →	+0.259	+1.793	<.001	<.001	3	16
STOMACH	Regulation of cell-substrate junction organization →	+0.105	+1.751	.001	.001	3	14
STOMACH	Positive regulation of cell-substrate junction organization →	+0.152	+2.262	<.001	<.001	3	14
BREAST	Positive regulation of focal adhesion assembly →	+0.128	+1.340	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of modification of synaptic structure →	+0.155	+1.607	.001	<.001	3	13
STOMACH	Positive regulation of hippo signaling →	+0.150	+2.031	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,446 associations by consensus.

Positive regulation of membrane tubulation by ASAP1 expression — URINARY_TRACT

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