ASAP1

Across TCGA cell cohorts, ASAP1 mutation is significantly associated with the RNA expression of many other genes, with 685 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASAP1-associated genes across cancer lineages are OR1P1, SIRPD, and CLLU1-AS1. Each is linked with ASAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASAP1-to-partner and partner-to-ASAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1P1 grouped by ASAP1-low versus ASAP1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAP1→partner) and Y-score (partner→ASAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1P1 →	+0.016	+4.415	<.001	.007	3	2
PANCREAS	SIRPD →	+0.270	+4.011	<.001	.009	3	1
PANCREAS	CLLU1-AS1 →	+0.048	+4.011	<.001	.009	3	1
SOFT_TISSUE	LYZL2 →	+0.018	+3.977	<.001	.007	3	1
SOFT_TISSUE	LRRC52 →	+0.012	+3.930	.006	.001	3	1
SOFT_TISSUE	C4orf50 →	+0.643	+3.691	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 685 associations by consensus.

OR1P1 by ASAP1 expression — SKIN

Explore this box plot interactively →