Across TCGA pan-cancer cohorts, ASAH2B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ASAH2B data layer compared with 26 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ASAH2B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASAH2B expression acts as an unfavorable survival marker.

BRCA are the cancer types where ASAH2B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	All	0.321	0.903	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ASAH2B tumor-vs-normal RNA expression · all ASAH2B data types