ASAH1

Across TCGA pan-cancer cohorts, ASAH1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASAH1 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ASAH1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASAH1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

COAD, HNSC, and PDAC are the cancer types where ASAH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.883	1.000	.020	24	view →
HNSC	DFS	Quartile	II,III,IV	0.906	1.000	.016	13	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	9	view →
GBM	OS	Quartile	All	0.400	0.642	.012	5	view →
CCRCC	DFS	Quartile	All	0.887	0.627	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASAH1–COAD (DFS)

Open the COAD breakdown →