ASAH1

Across TCGA patient cohorts, ASAH1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,817 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASAH1-associated genes across cancer lineages are HTRA4, ACP5, and PKD2L1. Each is linked with ASAH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ASAH1-to-partner and partner-to-ASAH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASAH1 versus HTRA4 in CCRCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAH1→partner) and Y-score (partner→ASAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HTRA4 →	+1.123	+0.472	<.001	<.001	3	7
GBM	ACP5 →	+1.029	+0.401	<.001	<.001	3	6
CCRCC	PKD2L1 →	+0.769	+0.488	<.001	<.001	3	6
GBM	APOC1 →	+1.229	+0.512	<.001	<.001	3	6
UCEC	MPP1 →	+0.928	+0.456	.005	<.001	3	6
HNSC	CTSS →	+1.285	+0.511	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,817 associations by consensus.

ASAH1 vs HTRA4 — CCRCC

Explore this scatter interactively →