ASAH1

Across TCGA patient cohorts, ASAH1 mutation is significantly associated with the RNA expression of many other genes, with 781 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASAH1-associated genes across cancer lineages are RN7SKP145, RNA5SP204, and RPL7P55. Each is linked with ASAH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ASAH1-to-partner and partner-to-ASAH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP145 grouped by ASAH1-low versus ASAH1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAH1→partner) and Y-score (partner→ASAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP145 →	+0.112	+5.251	<.001	.006	3	3
BLCA	RNA5SP204 →	+0.331	+6.444	<.001	.001	3	2
SKCM	RPL7P55 →	+0.057	+4.744	<.001	.001	3	2
COAD	MTCYBP45 →	+0.233	+5.734	<.001	<.001	3	2
UCEC	RNU6-728P →	+0.120	+2.920	.001	.008	3	2
UCEC	MIR194-1 →	+0.400	+1.987	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 781 associations by consensus.

RN7SKP145 by ASAH1 expression — BLCA

Explore this box plot interactively →