Across TCGA patient cohorts, AS3MT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible AS3MT-associated GO terms across cancer lineages are Smoothened signaling pathway, Piecemeal microautophagy of the nucleus, and Protein import into peroxisome matrix, receptor recycling. Each is linked with AS3MT in more than 23 cancer types. Because this analysis shows association rather than direction, both AS3MT-to-partner and partner-to-AS3MT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AS3MT→partner) and Y-score (partner→AS3MT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Smoothened signaling pathway →	+0.043	+0.232	<.001	<.001	3	24
TGCT	Piecemeal microautophagy of the nucleus →	+0.058	+0.372	<.001	<.001	3	23
THYM	Protein import into peroxisome matrix, receptor recycling →	+0.057	+0.306	<.001	<.001	3	22
TGCT	Regulation of smoothened signaling pathway →	+0.055	+0.444	<.001	<.001	3	22
THYM	Regulation of RNA export from nucleus →	+0.091	+0.336	<.001	<.001	3	21
ACC	Vesicle tethering involved in exocytosis →	+0.051	+1.511	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Exploration

AS3MT survival (RNA) · tumor vs normal (RNA) · all AS3MT data types