Across TCGA patient cohorts, AS3MT protein abundance is significantly associated with the RNA expression of many other genes, with 9,209 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AS3MT-associated genes across cancer lineages are CHST10, TMEM98, and HOGA1. Each is linked with AS3MT in more than 4 cancer types. Because this analysis shows association rather than direction, both AS3MT-to-partner and partner-to-AS3MT results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AS3MT→partner) and Y-score (partner→AS3MT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHST10 →	+0.749	+0.522	<.001	.002	3	5
HNSC	TMEM98 →	+1.073	+0.605	<.001	<.001	3	5
OV	HOGA1 →	+0.772	+0.426	.001	.003	3	5
GBM	TSPOAP1 →	+0.888	+0.394	<.001	.004	3	5
OV	LRP3 →	+0.878	+0.287	<.001	.002	2	5
UCEC	ARL3 →	+0.571	+0.614	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,209 associations by consensus.

Exploration

AS3MT survival (RNA) · tumor vs normal (RNA) · all AS3MT data types