ARV1

Across TCGA patient cohorts, ARV1 mutation is significantly associated with the RNA expression of many other genes, with 901 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARV1-associated genes across cancer lineages are RNU6-328P, DAOA, and RNU6-933P. Each is linked with ARV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARV1-to-partner and partner-to-ARV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-328P grouped by ARV1-low versus ARV1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARV1→partner) and Y-score (partner→ARV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-328P →	+0.618	+6.618	<.001	.001	3	2
UCEC	DAOA →	+0.089	+2.581	.001	.003	3	2
UCEC	RNU6-933P →	+0.522	+2.670	<.001	.001	3	2
UCEC	FDX1P2 →	+0.141	+2.801	.002	.005	3	2
UCEC	RNU6-1247P →	+0.454	+2.599	<.001	.009	3	2
UCEC	RNA5SP206 →	+0.760	+3.133	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 901 associations by consensus.

RNU6-328P by ARV1 expression — BLCA

Explore this box plot interactively →