ARTN

Across TCGA pan-cancer cohorts, ARTN mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARTN data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ARTN mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ARTN expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC, COAD, and GBM are the cancer types where ARTN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	1.000	0.552	.001	42	view →
COAD	DFS	Median	III,IV	0.717	1.000	.027	12	view →
GBM	DFS	Tertile	All	0.951	0.739	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARTN–UCEC (DFS)

Open the UCEC breakdown →