ART5

Across TCGA patient cohorts, ART5 mutation is significantly associated with the RNA expression of many other genes, with 2,829 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ART5-associated genes across cancer lineages are PSMB7P1, MIR8067, and AQP7P4. Each is linked with ART5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ART5-to-partner and partner-to-ART5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMB7P1 grouped by ART5-low versus ART5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ART5→partner) and Y-score (partner→ART5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PSMB7P1 →	+0.031	+3.732	<.001	.001	3	3
COAD	MIR8067 →	+0.589	+4.225	<.001	.007	3	2
CESC	AQP7P4 →	+0.086	+5.539	<.001	.004	3	2
CESC	SNORD116-3 →	+0.749	+5.103	<.001	.008	3	2
CESC	CCL27 →	+0.087	+5.812	<.001	.003	3	2
SKCM	NPRL2 →	+0.358	+2.555	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,829 associations by consensus.

PSMB7P1 by ART5 expression — SKCM

Explore this box plot interactively →