ARSL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARSL RNA expression is significantly associated with the protein abundance of many other proteins, with 13,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARSL-associated proteins across cancer lineages are SEPTIN11, ROCK2, and HEPH. Each is linked with ARSL in more than 4 cancer types. Because this analysis shows association rather than direction, both ARSL-to-partner and partner-to-ARSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARSL versus SEPTIN11 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSL→partner) and Y-score (partner→ARSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSEPTIN11 →+0.422+0.743<.001<.00135
COADROCK2 →+0.267+1.091<.001<.00135
OVHEPH →+0.910+1.115<.001<.00135
LSCCFKBP9 →+0.605+0.625<.001<.00135
OVSEPTIN2 →+0.191+0.699<.001<.00134
LSCCSEPTIN7 →+0.270+1.014<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,641 associations by consensus.

ARSL vs SEPTIN11 — LSCC

Per-sample scatter of ARSL vs SEPTIN11 in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration