ARSL

Across TCGA patient cohorts, ARSL protein abundance is significantly associated with the RNA expression of many other genes, with 5,542 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARSL-associated genes across cancer lineages are CCDC88A, ARHGDIG, and MXRA8. Each is linked with ARSL in more than 3 cancer types. Because this analysis shows association rather than direction, both ARSL-to-partner and partner-to-ARSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARSL versus CCDC88A in GBM, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSL→partner) and Y-score (partner→ARSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCDC88A →	-0.772	-0.747	<.001	<.001	3	4
PDAC	ARHGDIG →	+0.747	+0.658	<.001	.002	3	3
OV	MXRA8 →	+2.017	+1.456	<.001	<.001	3	3
GBM	CHAMP1 →	-0.551	-0.450	.001	.004	3	3
GBM	GSK3B →	-0.367	-0.375	.003	.008	3	3
PDAC	DNAJC13 →	-0.325	-0.663	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,542 associations by consensus.

ARSL vs CCDC88A — GBM

Explore this scatter interactively →