ARSH

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARSH protein abundance is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. OV shows the largest number of these associations.

The most reproducible ARSH-associated genes across cancer lineages are MMP9, STX1A, and PRLR. Each is linked with ARSH in more than 1 cancer types. Because this analysis shows association rather than direction, both ARSH-to-partner and partner-to-ARSH results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSH→partner) and Y-score (partner→ARSH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMMP9 →-2.499-1.654.004.00531
OVSTX1A →-0.900-1.654.002.00531
OVPRLR →-1.590-1.654.007.00531
OVUXS1 →+0.549+1.600<.001.00931
OVHPCAL4 →+0.364+1.600<.001.00931
OVDCLRE1B →-0.843-1.654.005.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

Exploration