Across TCGA patient cohorts, ARSH mutation is significantly associated with the RNA expression of many other genes, with 1,466 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARSH-associated genes across cancer lineages are ZNF77, RN7SL690P, and DTWD1. Each is linked with ARSH in more than 2 cancer types. Because this analysis shows association rather than direction, both ARSH-to-partner and partner-to-ARSH results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSH→partner) and Y-score (partner→ARSH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZNF77 →	+0.531	+3.832	<.001	<.001	3	3
SKCM	RN7SL690P →	+0.049	+2.449	<.001	.007	3	2
SKCM	DTWD1 →	+0.368	+2.328	.008	<.001	3	2
SKCM	EIF3J →	+0.515	+2.826	.007	.001	3	2
UCEC	FARSB →	+0.359	+3.470	.002	.002	3	2
SKCM	EPHX2 →	-0.810	-1.894	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,466 associations by consensus.

Exploration

ARSH survival (RNA) · tumor vs normal (RNA) · all ARSH data types