Across TCGA pan-cancer cohorts, ARSD Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ARSD data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ARSD Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARSD expression acts as an unfavorable survival marker.
KIRC, HNSC, and STAD are the cancer types where ARSD Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.