ARSD

Across TCGA cell cohorts, ARSD mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARSD-associated genes across cancer lineages are GALP, TAS2R60, and OR10S1. Each is linked with ARSD in more than 1 cancer types. Because this analysis shows association rather than direction, both ARSD-to-partner and partner-to-ARSD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by ARSD-low versus ARSD-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSD→partner) and Y-score (partner→ARSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GALP →	+0.027	+5.201	.005	.006	3	1
SKIN	TAS2R60 →	+0.069	+4.415	<.001	.007	3	1
SKIN	OR10S1 →	+0.099	+4.415	<.001	.007	3	1
SKIN	NEXMIF →	+0.125	+4.095	<.001	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	TRARG1 →	+0.021	+3.760	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GALP by ARSD expression — BLOOD_Leukemia

Explore this box plot interactively →