ARSA

Across TCGA cell cohorts, ARSA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,130 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ARSA-associated GO terms across cancer lineages are Glycerophospholipid metabolic process, COPI-coated vesicle budding, and Golgi transport vesicle coating. Each is linked with ARSA in more than 13 cancer types. Because this analysis shows association rather than direction, both ARSA-to-partner and partner-to-ARSA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerophospholipid metabolic process grouped by ARSA-low versus ARSA-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSA→partner) and Y-score (partner→ARSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Glycerophospholipid metabolic process →	+0.039	+1.061	.001	<.001	3	14
OESOPHAGUS	COPI-coated vesicle budding →	+0.125	+1.067	.005	.006	3	14
OESOPHAGUS	Golgi transport vesicle coating →	+0.125	+1.067	.005	.006	3	14
OESOPHAGUS	COPI coating of Golgi vesicle →	+0.125	+1.067	.005	.006	3	14
BONE	ERAD pathway →	+0.081	+1.252	.008	.005	2	14
CNS	Glycoprotein catabolic process →	+0.149	+1.162	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,130 associations by consensus.

Glycerophospholipid metabolic process by ARSA expression — SKIN

Explore this box plot interactively →