Across TCGA patient cohorts, ARRDC5 mutation is significantly associated with the RNA expression of many other genes, with 573 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARRDC5-associated genes across cancer lineages are MIR6803, UHRF1, and RNU6-768P. Each is linked with ARRDC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARRDC5-to-partner and partner-to-ARRDC5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC5→partner) and Y-score (partner→ARRDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.183	+4.777	<.001	.002	3	3
UCEC	UHRF1 →	+1.087	+2.711	<.001	.003	3	2
HNSC	RNU6-768P →	+0.392	+6.936	<.001	<.001	3	2
UCEC	COPS3 →	+0.577	+2.627	.001	.005	3	2
UCEC	CEP78 →	+0.549	+2.700	.004	.006	3	2
UCEC	SAPCD2 →	+0.781	+3.332	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 573 associations by consensus.

Exploration

ARRDC5 survival (RNA) · tumor vs normal (RNA) · all ARRDC5 data types