Across TCGA cell cohorts, ARRDC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,206 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARRDC5-associated GO terms across cancer lineages are Phosphatidylglycerol metabolic process, Plasma membrane organization, and Regulation of protein modification by small protein conjugation or removal. Each is linked with ARRDC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARRDC5-to-partner and partner-to-ARRDC5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC5→partner) and Y-score (partner→ARRDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Phosphatidylglycerol metabolic process →	-0.068	-0.008	<.001	.004	3	6
OESOPHAGUS	Plasma membrane organization →	+0.105	+0.035	.004	.002	3	5
STOMACH	Regulation of protein modification by small protein conjugation or removal →	+0.064	+0.019	<.001	.002	3	5
STOMACH	Negative regulation of canonical NF-kappaB signal transduction →	+0.038	+0.012	.007	.009	3	5
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.051	+0.030	.001	.001	3	5
LUNG_NSCLC_LUAD	Rho protein signal transduction →	+0.086	+0.023	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,206 associations by consensus.

Exploration

ARRDC5 survival (RNA) · tumor vs normal (RNA) · all ARRDC5 data types