ARRDC4

Across TCGA patient cohorts, ARRDC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,047 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARRDC4-associated proteins across cancer lineages are MRPS7, CLPX, and DDX27. Each is linked with ARRDC4 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARRDC4-to-partner and partner-to-ARRDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRDC4 versus MRPS7 in COAD, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC4→partner) and Y-score (partner→ARRDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRPS7 →	-0.320	-0.484	<.001	<.001	3	7
OV	CLPX →	-0.303	-0.853	<.001	<.001	3	6
BRCA	DDX27 →	-0.391	-0.613	<.001	.001	3	6
BRCA	MRPS26 →	-0.317	-0.635	<.001	<.001	3	6
OV	MSH6 →	-0.583	-1.031	<.001	<.001	3	6
LSCC	TXNIP →	+0.450	+0.589	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,047 associations by consensus.

ARRDC4 vs MRPS7 — COAD

Explore this scatter interactively →