ARRDC4

Across TCGA patient cohorts, ARRDC4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARRDC4-associated genes across cancer lineages are GJA5, CD69, and IL1R1. Each is linked with ARRDC4 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARRDC4-to-partner and partner-to-ARRDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRDC4 versus GJA5 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC4→partner) and Y-score (partner→ARRDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GJA5 →	-0.940	-0.656	<.001	.001	3	5
LSCC	CD69 →	-1.074	-0.609	.001	.008	3	4
BRCA	IL1R1 →	-1.186	-0.617	<.001	<.001	3	4
BRCA	PLXDC2 →	-1.239	-0.902	<.001	<.001	3	4
LSCC	GIMAP6 →	-0.864	-0.795	<.001	<.001	3	4
LSCC	CLEC1A →	-0.713	-0.825	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,088 associations by consensus.

ARRDC4 vs GJA5 — BRCA

Explore this scatter interactively →