ARRDC3-AS1

Across TCGA pan-cancer cohorts, ARRDC3-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ARRDC3-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ARRDC3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARRDC3-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CHOL show a favorable association.

UVM, LGG, and ACC are the cancer types where ARRDC3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Quartile	All	0.437	0.936	<.001	90	view →
LGG	DFS	Median	All	0.668	0.806	<.001	51	view →
ACC	OS	Median	All	0.457	0.806	<.001	44	view →
KICH	DFS	Tertile	All	0.740	1.000	.004	33	view →
BRCA	OS	Median	IV	0.847	0.348	.002	25	view →
CHOL	DFS	Median	All	0.729	0.234	<.001	16	view →
READ	OS	Tertile	III,IV	1.000	0.368	.005	13	view →
KIRP	DFS	Quartile	All	0.897	0.527	.009	12	view →
PCPG	OS	Median	All	0.937	1.000	.020	11	view →
HNSC	DFS	Quartile	IV	0.701	0.453	.003	7	view →
KIRC	DFS	Tertile	IV	0.332	0.593	.028	6	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ARRDC3-AS1–UVM (OS)

Open the UVM breakdown →