ARRDC2

Across TCGA patient cohorts, ARRDC2 protein abundance is significantly associated with the RNA expression of many other genes, with 933 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARRDC2-associated genes across cancer lineages are NFKBIA, DOK5, and PDYN. Each is linked with ARRDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARRDC2-to-partner and partner-to-ARRDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRDC2 versus NFKBIA in PDAC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC2→partner) and Y-score (partner→ARRDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NFKBIA →	+0.512	+1.242	<.001	<.001	3	1
PDAC	DOK5 →	-0.942	-1.270	.001	.002	3	1
PDAC	PDYN →	+0.048	+1.569	<.001	<.001	3	1
PDAC	PIN4 →	-0.297	-1.321	.001	<.001	3	1
PDAC	FGF14 →	-0.763	-1.503	.002	<.001	3	1
PDAC	NCAPD2 →	+0.408	+0.814	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 933 associations by consensus.

ARRDC2 vs NFKBIA — PDAC

Explore this scatter interactively →