Across TCGA patient cohorts, ARRDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,963 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARRDC1-associated proteins across cancer lineages are BSPRY, SH3GLB2, and NIBAN2. Each is linked with ARRDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARRDC1-to-partner and partner-to-ARRDC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC1→partner) and Y-score (partner→ARRDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BSPRY →	+0.573	+0.349	<.001	.009	3	6
PDAC	SH3GLB2 →	+0.303	+0.455	<.001	<.001	3	6
OV	NIBAN2 →	+0.422	+0.600	.001	<.001	3	5
CCRCC	PRDX4 →	-0.317	-0.277	.003	.003	3	5
GBM	P4HB →	-0.372	-0.336	<.001	<.001	3	5
LUAD	HSP90B1 →	-0.399	-0.412	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,963 associations by consensus.

Exploration

ARRDC1 survival (RNA) · tumor vs normal (RNA) · all ARRDC1 data types