Across TCGA patient cohorts, ARRDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,406 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARRDC1-associated genes across cancer lineages are RIPK3, GPC2, and MEX3A. Each is linked with ARRDC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARRDC1-to-partner and partner-to-ARRDC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC1→partner) and Y-score (partner→ARRDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RIPK3 →	+0.638	+0.266	<.001	<.001	3	4
GBM	GPC2 →	-1.040	-0.256	<.001	.002	3	4
GBM	MEX3A →	-1.359	-0.237	<.001	<.001	3	4
BRCA	CMSS1 →	-0.436	-0.165	.003	.007	3	4
GBM	NKG7 →	+1.057	+0.346	<.001	<.001	3	4
GBM	PRF1 →	+1.229	+0.226	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,406 associations by consensus.

Exploration

ARRDC1 survival (RNA) · tumor vs normal (RNA) · all ARRDC1 data types