Across TCGA patient cohorts, ARRDC1 mutation is significantly associated with the RNA expression of many other genes, with 290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARRDC1-associated genes across cancer lineages are SRGNP1, PPP1R26P2, and RNU6-275P. Each is linked with ARRDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARRDC1-to-partner and partner-to-ARRDC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC1→partner) and Y-score (partner→ARRDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SRGNP1 →	+0.056	+5.729	<.001	<.001	3	2
BLCA	PPP1R26P2 →	+0.005	+4.985	<.001	.002	3	2
COAD	RNU6-275P →	+0.278	+5.734	<.001	<.001	3	2
COAD	MIR8055 →	+1.208	+3.758	<.001	.006	3	2
BLCA	HIGD1AP13 →	+0.069	+4.492	<.001	.005	3	2
BRCA	MIR6846 →	+0.351	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 290 associations by consensus.

Exploration

ARRDC1 survival (RNA) · tumor vs normal (RNA) · all ARRDC1 data types