ARRB2

Across TCGA patient cohorts, ARRB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,787 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARRB2-associated proteins across cancer lineages are DOCK2, FERMT3, and FMNL1. Each is linked with ARRB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARRB2-to-partner and partner-to-ARRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRB2 versus DOCK2 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRB2→partner) and Y-score (partner→ARRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOCK2 →	+0.694	+0.701	<.001	<.001	3	10
GBM	FERMT3 →	+0.667	+0.638	<.001	<.001	3	10
GBM	FMNL1 →	+0.667	+0.684	<.001	<.001	3	10
GBM	HCK →	+0.781	+0.755	<.001	<.001	3	10
GBM	ITGAL →	+0.569	+0.705	<.001	<.001	3	10
OV	LCP2 →	+0.514	+0.545	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,787 associations by consensus.

ARRB2 vs DOCK2 — GBM

Explore this scatter interactively →