ARRB2

Across TCGA patient cohorts, ARRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,197 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARRB2-associated genes across cancer lineages are MYO1F, LILRB3, and PRAM1. Each is linked with ARRB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARRB2-to-partner and partner-to-ARRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRB2 versus MYO1F in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRB2→partner) and Y-score (partner→ARRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.927	+0.298	<.001	<.001	3	10
COAD	LILRB3 →	+1.056	+0.333	<.001	<.001	3	10
GBM	PRAM1 →	+0.764	+0.362	<.001	<.001	3	9
HNSC	CYTH4 →	+1.079	+0.254	<.001	<.001	3	9
GBM	CSF2RB →	+1.097	+0.334	<.001	<.001	3	9
UCEC	SIRPB1 →	+0.676	+0.291	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,197 associations by consensus.

ARRB2 vs MYO1F — GBM

Explore this scatter interactively →