ARRB2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARRB2 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,106 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARRB2-associated proteins across cancer lineages are ARHGAP9, LCP2, and MYO1F. Each is linked with ARRB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARRB2-to-partner and partner-to-ARRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARRB2 versus ARHGAP9 in GBM, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRB2→partner) and Y-score (partner→ARRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMARHGAP9 →+0.657+0.322<.001<.001310
HNSCLCP2 →+0.597+0.326<.001<.001310
GBMMYO1F →+0.799+0.387<.001<.001310
GBMMYO1G →+0.763+0.355<.001<.001310
HNSCARHGAP25 →+0.699+0.389<.001<.00139
GBMARHGAP30 →+0.706+0.283<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,106 associations by consensus.

ARRB2 vs ARHGAP9 — GBM

Per-sample scatter of ARRB2 vs ARHGAP9 in GBM (Pearson r = 0.64).

Explore this scatter interactively →

Exploration