ARRB2

Across TCGA patient cohorts, ARRB2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARRB2-associated genes across cancer lineages are mv Endothelial cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with ARRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARRB2-to-partner and partner-to-ARRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by ARRB2-low versus ARRB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRB2→partner) and Y-score (partner→ARRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mv Endothelial cells →	-0.028	-3.459	.005	.005	3	1
UCEC	Endothelial cells →	-0.041	-3.313	.011	.010	2	1
UCEC	lymphatic Endothelial cells →	-0.026	-2.168	.008	.011	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

mv Endothelial cells by ARRB2 expression — UCEC

Explore this box plot interactively →