ARRB1

Across TCGA patient cohorts, ARRB1 mutation is significantly associated with the RNA expression of many other genes, with 2,537 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARRB1-associated genes across cancer lineages are LINC02118, RN7SKP152, and DNAJA1P1. Each is linked with ARRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARRB1-to-partner and partner-to-ARRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02118 grouped by ARRB1-low versus ARRB1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRB1→partner) and Y-score (partner→ARRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02118 →	+0.152	+5.669	<.001	.003	3	2
CESC	RN7SKP152 →	+0.258	+6.569	<.001	.001	3	2
CESC	DNAJA1P1 →	+0.047	+5.306	<.001	.006	3	2
COAD	RNA5SP435 →	+0.604	+4.196	.008	.001	3	2
COAD	RN7SKP76 →	+0.258	+4.225	<.001	.007	3	2
COAD	RNU6-142P →	+0.966	+4.225	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,537 associations by consensus.

LINC02118 by ARRB1 expression — CESC

Explore this box plot interactively →