Across TCGA pan-cancer cohorts, ARPP19P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ARPP19P2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ARPP19P2 RNA is repressed in tumor relative to normal tissue. In most cancer types ARPP19P2 is over-expressed in tumor, although a few such as KIRP and LUSC show the opposite, repressed pattern.

KIRP, LUSC, and LUAD are the cancer types where ARPP19P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARPP19P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.040	.019	3	view →
LUSC	Female	II,III,IV	−0.182	.038	2	view →
LUAD	All	All	+0.063	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ARPP19P2 RNA expression & survival · all ARPP19P2 data types