ARPIN

Across TCGA patient cohorts, ARPIN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,714 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARPIN-associated proteins across cancer lineages are MTHFD2, SRP54, and IQGAP1. Each is linked with ARPIN in more than 4 cancer types. Because this analysis shows association rather than direction, both ARPIN-to-partner and partner-to-ARPIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARPIN versus MTHFD2 in BRCA, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPIN→partner) and Y-score (partner→ARPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MTHFD2 →	-0.698	-0.811	<.001	<.001	3	5
LSCC	SRP54 →	-0.245	-0.403	<.001	<.001	3	5
LSCC	IQGAP1 →	+0.245	+0.455	<.001	<.001	3	5
BRCA	RPL3 →	-0.376	-0.719	<.001	<.001	3	5
BRCA	GRPEL1 →	-0.443	-0.575	<.001	<.001	3	5
HNSC	PTPN9 →	+0.252	+0.657	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,714 associations by consensus.

ARPIN vs MTHFD2 — BRCA

Explore this scatter interactively →