ARPIN

Across TCGA patient cohorts, ARPIN mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARPIN-associated genes across cancer lineages are Mast cells, pDC, and B-cells. Each is linked with ARPIN in more than 1 cancer types. Because this analysis shows association rather than direction, both ARPIN-to-partner and partner-to-ARPIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mast cells grouped by ARPIN-low versus ARPIN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPIN→partner) and Y-score (partner→ARPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mast cells →	+0.027	+2.042	<.001	.018	3	1
UCEC	pDC →	+0.073	+1.882	<.001	.031	3	1
PRAD	B-cells →	+0.052	+3.851	.046	.040	3	1
UCEC	MEP →	+0.034	+2.010	.006	.019	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Mast cells by ARPIN expression — UCEC

Explore this box plot interactively →