ARPC5

Across TCGA cell cohorts, ARPC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ARPC5-associated GO terms across cancer lineages are Negative regulation of amino acid biosynthetic process, Negative regulation of amino acid metabolic process, and Peptidyl-arginine modification. Each is linked with ARPC5 in more than 11 cancer types. Because this analysis shows association rather than direction, both ARPC5-to-partner and partner-to-ARPC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of amino acid biosynthetic process grouped by ARPC5-low versus ARPC5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC5→partner) and Y-score (partner→ARPC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of amino acid biosynthetic process →	+0.404	+0.828	<.001	.001	3	12
BONE	Negative regulation of amino acid metabolic process →	+0.404	+0.828	<.001	.001	3	12
LARGE_INTESTINE	Peptidyl-arginine modification →	-0.115	-0.750	<.001	<.001	3	12
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.066	+0.902	<.001	.001	3	10
BONE	Retrograde transport, endosome to Golgi →	+0.072	+0.659	.004	.006	3	10
BONE	Regulation of amino acid metabolic process →	+0.235	+0.775	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Negative regulation of amino acid biosynthetic process by ARPC5 expression — BONE

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