ARPC3P4

Across TCGA pan-cancer cohorts, ARPC3P4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ARPC3P4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ARPC3P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARPC3P4 is over-expressed in tumor.

KIRC, BLCA, and COAD are the cancer types where ARPC3P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARPC3P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.217	<.001	9	view →
BLCA	All	III,IV	+0.222	.020	6	view →
COAD	All	All	+0.178	.002	6	view →
LUAD	All	All	+0.363	<.001	4	view →
CHOL	All	II,III,IV	+0.620	.035	3	view →
LIHC	All	All	+0.072	.009	2	view →
READ	Female	All	+0.396	<.001	1	view →
LUSC	All	All	+0.132	.030	1	view →
HNSC	All	II,III,IV	+0.079	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ARPC3P4–KIRC

Open the KIRC breakdown →