ARPC3P3

Across TCGA pan-cancer cohorts, ARPC3P3 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ARPC3P3 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ARPC3P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARPC3P3 expression acts as an unfavorable survival marker, although some lineages such as CESC and THCA show a favorable association.

UVM, CESC, and MESO are the cancer types where ARPC3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.566	0.904	<.001	128	view →
CESC	OS	Tertile	All	0.893	0.704	<.001	100	view →
MESO	OS	Tertile	All	0.353	0.678	.001	72	view →
LIHC	OS	Median	III,IV	0.183	0.557	<.001	65	view →
KICH	DFS	Median	III,IV	0.297	1.000	.002	54	view →
LUAD	OS	Tertile	III,IV	0.491	0.803	.005	53	view →
LGG	DFS	Median	All	0.653	0.825	<.001	46	view →
THCA	OS	Quartile	All	1.000	0.981	.009	31	view →
PAAD	OS	Median	All	0.239	0.485	.002	21	view →
HNSC	DFS	Tertile	All	0.630	0.747	.008	20	view →
SKCM	OS	Quartile	III,IV	0.989	0.757	.005	19	view →
READ	DFS	Median	III,IV	0.863	0.628	.003	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ARPC3P3–UVM (DFS)

Open the UVM breakdown →