ARNTL2

Across TCGA cell cohorts, ARNTL2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARNTL2-associated genes across cancer lineages are FCRL4 and GSG1L2. Each is linked with ARNTL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARNTL2-to-partner and partner-to-ARNTL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCRL4 grouped by ARNTL2-low versus ARNTL2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARNTL2→partner) and Y-score (partner→ARNTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FCRL4 →	+0.013	+4.906	<.001	.006	3	1
LARGE_INTESTINE	GSG1L2 →	+0.020	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FCRL4 by ARNTL2 expression — OESOPHAGUS

Explore this box plot interactively →