ARNTL2-AS1

Across TCGA pan-cancer cohorts, ARNTL2-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ARNTL2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ARNTL2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARNTL2-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BRCA show a favorable association.

KIRC, LIHC, and KICH are the cancer types where ARNTL2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.715	0.836	<.001	152	view →
LIHC	DFS	Tertile	All	0.189	0.356	<.001	60	view →
KICH	DFS	Tertile	All	0.640	1.000	<.001	59	view →
SKCM	DFS	Tertile	III,IV	0.331	0.663	<.001	39	view →
THYM	DFS	Quartile	All	0.721	0.973	<.001	36	view →
UCEC	DFS	Tertile	All	0.532	0.713	.007	36	view →
MESO	OS	Median	All	0.283	0.490	.003	31	view →
ACC	DFS	Tertile	III,IV	0.010	0.364	<.001	27	view →
PAAD	DFS	Tertile	All	0.369	0.590	.001	26	view →
LUAD	OS	Quartile	All	0.734	0.848	.003	22	view →
LUSC	OS	Quartile	II,III,IV	0.807	0.598	.003	22	view →
CESC	OS	Tertile	All	0.486	0.782	.007	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ARNTL2-AS1–KIRC (OS)

Open the KIRC breakdown →