ARNT2

Across TCGA cell cohorts, ARNT2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARNT2-associated genes across cancer lineages are TGM6, OR10T2, and OR10R2. Each is linked with ARNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARNT2-to-partner and partner-to-ARNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM6 grouped by ARNT2-low versus ARNT2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARNT2→partner) and Y-score (partner→ARNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TGM6 →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	OR10T2 →	+1.075	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR10R2 →	+2.428	+4.551	<.001	.004	3	1
LARGE_INTESTINE	FAM205A →	+0.027	+3.252	<.001	<.001	3	1
LARGE_INTESTINE	COX10 →	+0.722	+3.064	<.001	.009	3	1
SKIN	ADAM2 →	+0.004	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TGM6 by ARNT2 expression — BLOOD_Leukemia

Explore this box plot interactively →