ARMH4

Across TCGA patient cohorts, ARMH4 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMH4-associated genes across cancer lineages are Annexin_VII, EGFR_pY1068, and FoxM1. Each is linked with ARMH4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMH4-to-partner and partner-to-ARMH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin_VII grouped by ARMH4-low versus ARMH4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMH4→partner) and Y-score (partner→ARMH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Annexin_VII →	-0.118	-3.142	.032	.019	3	2
UCEC	EGFR_pY1068 →	-0.171	-1.415	.015	.040	3	2
UCEC	FoxM1 →	+0.165	+1.273	.023	.007	3	2
UCEC	p27_pT198 →	+0.068	+1.273	.024	.007	3	2
UCEC	PCNA →	+0.138	+1.392	.023	.017	3	2
UCEC	PDCD4 →	-0.384	-1.727	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Annexin_VII by ARMH4 expression — LUSC

Explore this box plot interactively →