Across TCGA patient cohorts, ARMCX6 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMCX6-associated genes across cancer lineages are EGFR_pY1068, ERK2, and JNK2. Each is linked with ARMCX6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX6-to-partner and partner-to-ARMCX6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX6→partner) and Y-score (partner→ARMCX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.310	-3.321	.004	.009	3	1
UCEC	ERK2 →	+0.197	+3.321	.019	.010	3	1
UCEC	JNK2 →	+0.199	+2.817	.022	.036	3	1
UCEC	Ku80 →	+0.216	+1.598	.036	.044	3	1
UCEC	MEK1_p_S217_S221 →	-0.311	-2.115	.009	.019	3	1
UCEC	Notch1 →	+0.154	+2.331	.012	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ARMCX6 survival (RNA) · tumor vs normal (RNA) · all ARMCX6 data types