ARMCX5

Across TCGA patient cohorts, ARMCX5 mutation is significantly associated with the RNA expression of many other genes, with 2,980 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMCX5-associated genes across cancer lineages are RN7SKP135, RNA5SP210, and FEM1AP3. Each is linked with ARMCX5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMCX5-to-partner and partner-to-ARMCX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP135 grouped by ARMCX5-low versus ARMCX5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX5→partner) and Y-score (partner→ARMCX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP135 →	+0.031	+4.311	<.001	.002	3	3
SKCM	RNA5SP210 →	+0.226	+3.578	.003	.001	3	3
BLCA	FEM1AP3 →	+0.038	+6.147	<.001	.002	3	2
LUSC	MIR28 →	+0.355	+4.853	<.001	.004	3	2
UCEC	DHRS11 →	+0.555	+3.839	<.001	<.001	3	2
UCEC	TCAIM →	+0.369	+1.684	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,980 associations by consensus.

RN7SKP135 by ARMCX5 expression — UCEC

Explore this box plot interactively →