ARMCX5

Across TCGA cell cohorts, ARMCX5 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ARMCX5-associated genes across cancer lineages are ASB17, GPR101, and HS3ST4. Each is linked with ARMCX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX5-to-partner and partner-to-ARMCX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by ARMCX5-low versus ARMCX5-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX5→partner) and Y-score (partner→ARMCX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	GPR101 →	+0.012	+3.990	.003	.003	3	1
OVARY	HS3ST4 →	+0.055	+3.662	.008	.009	3	1
OVARY	PPIAL4A →	+0.054	+3.657	<.001	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.025	+4.614	<.001	.002	3	1
OVARY	LRFN2 →	+0.020	+4.754	.004	.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ASB17 by ARMCX5 expression — OVARY

Explore this box plot interactively →