ARMCX4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARMCX4 mutation is significantly associated with the RNA expression of many other genes, with 353 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMCX4-associated genes across cancer lineages are KCNA10, MYOD1, and CCDC172. Each is linked with ARMCX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX4-to-partner and partner-to-ARMCX4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX4→partner) and Y-score (partner→ARMCX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaKCNA10 →+0.009+4.539<.001.00732
LUNG_NSCLC_LUSCMYOD1 →+0.046+4.108.006.00531
LUNG_NSCLC_LUSCCCDC172 →+0.023+4.108.004.00531
LUNG_NSCLC_LUSCNYX →+0.030+4.108.007.00531
LUNG_NSCLC_LUSCGAGE10 →+0.060+4.108<.001.00531
LUNG_NSCLC_LUSCWNT8A →+0.054+4.108<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 353 associations by consensus.

Exploration